(Actin Related Protein 2/3 Complex, Subunit 4, 20kDa (ARPC4))
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010].
Schrank, Aparicio, Li, Chang, Chait, Gundersen, Gottesman, Gautier: "Nuclear ARP2/3 drives DNA break clustering for homology-directed repair." in: Nature, Vol. 559, Issue 7712, pp. 61-66, (2018) (PubMed).
Rosentreter, Hofmann, Xavier, Stumpf, Noegel, Clemen: "Coronin 3 involvement in F-actin-dependent processes at the cell cortex." in: Experimental cell research, Vol. 313, Issue 5, pp. 878-95, (2007) (PubMed).
Anastasiadis, Moon, Thoreson, Mariner, Crawford, Zheng, Reynolds: "Inhibition of RhoA by p120 catenin." in: Nature cell biology, Vol. 2, Issue 9, pp. 637-44, (2001) (PubMed).
Defacque, Egeberg, Habermann, Diakonova, Roy, Mangeat, Voelter, Marriott, Pfannstiel, Faulstich, Griffiths: "Involvement of ezrin/moesin in de novo actin assembly on phagosomal membranes." in: The EMBO journal, Vol. 19, Issue 2, pp. 199-212, (2000) (PubMed).
Aliases for ARPC4 抗体
actin related protein 2/3 complex subunit 4 (ARPC4) 抗体 Actin-related protein 2/3 complex subunit 4 (PTRG_00644) 抗体 actin-related protein 2/3 complex subunit 4 (CMU_000110) 抗体 actin related protein 2/3 complex, subunit 4 (Arpc4) 抗体 actin related protein 2/3 complex subunit 4 (arpc4) 抗体 actin related protein 2/3 complex subunit 4 S homeolog (arpc4.S) 抗体 actin related protein 2/3 complex, subunit 4, 20kDa (ARPC4) 抗体 actin related protein 2/3 complex, subunit 4 (arpc4) 抗体 actin related protein 2/3 complex subunit 4 (Arpc4) 抗体 20kDa 抗体 5330419I20Rik 抗体 AI327076 抗体 ARC20 抗体 arc20 抗体 ARPC4 抗体 fa07b12 抗体 P20-ARC 抗体 p20-Arc 抗体 p20-arc 抗体 wu:fa07b12 抗体 zgc:77932 抗体