APOBEC3H 抗体
(Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H))
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009].
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Latest Publications for our APOBEC3H 抗体
: "Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease." in: Nature communications, Vol. 9, Issue 1, pp. 4137, (2019) (PubMed).: "The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H." in: Journal of molecular biology, Vol. 431, Issue 24, pp. 5019-5031, (2019) (PubMed).
: "APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction." in: Molecular and cellular biology, Vol. 38, Issue 23, (2018) (PubMed).
: "The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis." in: Nature communications, Vol. 7, pp. 12918, (2016) (PubMed).
: "The Structural Interface between HIV-1 Vif and Human APOBEC3H." in: Journal of virology, Vol. 91, Issue 5, (2016) (PubMed).
: "Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity." in: PLoS genetics, Vol. 10, Issue 11, pp. e1004761, (2014) (PubMed).
: "The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism." in: Molecular cell, Vol. 69, Issue 1, pp. 75-86.e9 (PubMed).
Aliases for APOBEC3H 抗体
apolipoprotein B mRNA editing enzyme catalytic subunit 3H (APOBEC3H) 抗体A3H 抗体
APOBEC3A 抗体
ARP10 抗体
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