(Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3D (APOBEC3D))
This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008].
Stenglein, Harris: "APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 16837-41, (2006) (PubMed).
Aliases for APOBEC3D 抗体
apolipoprotein B mRNA editing enzyme catalytic subunit 3D (APOBEC3D) 抗体 A3D 抗体 APOBEC3D 抗体 APOBEC3DE 抗体 APOBEC3E 抗体 ARP6 抗体