PPP2R4 抗体
(2 references)Quick Overview for PPP2R4 抗体 (ABIN969557)
抗原
See all PPP2R4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- PPP2R4 Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human PPP2R4 expressed in E. Coli.
-
亚型
- IgG1
-
-
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-323) antibody
PPP2R4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-323) antibodyPPP2R4 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-309) antibodyPPP2R4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) antibodyPPP2R4 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 小鼠 Monoclonal 4D9 unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-250) antibodyPPP2R4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) antibodyPPP2R4 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-323) antibodyPPP2R4 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 21-120) antibodyPPP2R4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (Center) antibodyPPP2R4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (C-Term) antibodyVerified PPP2R4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 874-84, (2010) (PubMed).
: "Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1140-52, (2010) (PubMed).
-
: "Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 874-84, (2010) (PubMed).
-
- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
-
别名
- PPP2R4
-
背景
- Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
-
分子量
- 41 kDa
-
基因ID
- 5524
-
UniProt
- Q15257
-
途径
- PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades
抗原
-
