PPP2R4 抗体
(2 references)-
- 抗原 See all PPP2R4 抗体
- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PPP2R4 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- PPP2R4 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PPP2R4 expressed in E. Coli.
- 克隆位点
- 4D9
- 亚型
- IgG1
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anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-323) antibody
PPP2R4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-323) antibodyPPP2R4 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-309) antibodyPPP2R4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) antibodyPPP2R4 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 小鼠 Monoclonal 4D9 unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-250) antibodyPPP2R4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) antibodyPPP2R4 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-323) antibodyPPP2R4 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 21-120) antibodyPPP2R4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (Center) antibodyPPP2R4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) (AA 1-323) antibodyPPP2R4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 874-84, (2010) (PubMed).
: "Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1140-52, (2010) (PubMed).
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: "Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 874-84, (2010) (PubMed).
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- 抗原
- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
- 别名
- PPP2R4 (PPP2R4 产品)
- 背景
- Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
- 分子量
- 41 kDa
- 基因ID
- 5524
- UniProt
- Q15257
- 途径
- PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades
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