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NCK1 抗体

This anti-NCK1 antibody is a 小鼠 单克隆 antibody detecting NCK1 in WB, IHC, ELISA 和 FACS. Suitable for 人 和 猴. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969545
发货至: 中国

Quick Overview for NCK1 抗体 (ABIN969545)

抗原

See all NCK1 抗体
NCK1 (NCK Adaptor Protein 1 (NCK1))

适用

  • 66
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  • 2
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  • 1
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人, 猴

宿主

  • 59
  • 6
  • 1
小鼠

克隆类型

  • 51
  • 15
单克隆

标记

  • 35
  • 5
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  • 3
  • 3
  • 3
  • 3
  • 2
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  • 2
This NCK1 antibody is un-conjugated

应用范围

  • 45
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  • 9
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  • 2
  • 1
  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

5B7
  • 原理

    NCK1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human NCK1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Preisinger, Kolch: "The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway." in: Cellular signalling, Vol. 22, Issue 5, pp. 848-56, (2010) (PubMed).

    Blasutig, New, Thanabalasuriar, Dayarathna, Goudreault, Quaggin, Li, Gruenheid, Jones, Pawson: "Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization." in: Molecular and cellular biology, Vol. 28, Issue 6, pp. 2035-46, (2008) (PubMed).

  • 抗原

    NCK1 (NCK Adaptor Protein 1 (NCK1))

    别名

    NCK1

    背景

    The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.

    分子量

    47 kDa

    UniProt

    P16333

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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