HSP90AA1 抗体
Quick Overview for HSP90AA1 抗体 (ABIN969528)
抗原
See all HSP90AA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HSP90AA1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human HSP90AA1 expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells." in: Molecular biology of the cell, Vol. 21, Issue 9, pp. 1462-9, (2010) (PubMed).
: "Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non-small cell lung cancer." in: Molecular cancer therapeutics, Vol. 8, Issue 12, pp. 3296-306, (2009) (PubMed).
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: "HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells." in: Molecular biology of the cell, Vol. 21, Issue 9, pp. 1462-9, (2010) (PubMed).
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- HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))
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别名
- HSP90AA1
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背景
- HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1, MIM 191175) and mitochondria (TRAP1, MIM 606219) (Chen et al., 2005 [PubMed 16269234]).
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分子量
- 90 kDa
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UniProt
- P07900
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途径
- M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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