我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Doublecortin 抗体 (AA 362-411)

Name: Doublecortin 抗体 (AA 362-411)
Brand: antibodies-online
SKU: ABIN969513
Availability: OutOfStock

This anti-Doublecortin antibody is a 小鼠单克隆 antibody detecting Doublecortin in WB, ELISA, IHC, ICC 和 FACS. Suitable for 人. This Primary Antibody has been cited in 1 publication.

Western blot analysis using DCX mouse mAb against Mouse heart (1) lysate. (Doublecortin 抗体 (AA 362-411))

Western blot analysis using DCX mAb against human DCX recombinant protein. (Doublecortin 抗体 (AA 362-411))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Doublecortin 抗体 (AA 362-411))

ELISA

Flow cytometric analysis of SK-N-SH cells using DCX mouse mAb (green) and negative control (red). (Doublecortin 抗体 (AA 362-411))

FACS

Immunofluorescence analysis of HepG2 cells using DCX mouse mAb (green). (Doublecortin 抗体 (AA 362-411))

Immunohistochemical analysis of paraffin-embedded brain tissue tissues using DCX mouse mAb with DAB staining. (Doublecortin 抗体 (AA 362-411))

IHC

Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using DCX mouse mAb with DAB staining. (Doublecortin 抗体 (AA 362-411))

IHC

7 images

(1 reference)

产品编号 ABIN969513

发货至: 中国

Datasheet as PDF

Quick Overview for Doublecortin 抗体 (AA 362-411) (ABIN969513)

抗原

See all Doublecortin (DCX) 抗体

Doublecortin (DCX)

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Doublecortin antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

2G5

抗原表位
7

5

5

4

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 362-411

原理

DCX Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human DCX (AA: 362-411) expressed in E. Coli.

亚型

IgG1
anti-Doublecortin (DCX) (AA 232-242) antibody
Verified DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Doublecortin (DCX) (AA 362-411) antibody
DCX 适用: 人 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

anti-Doublecortin (DCX) (AA 69-81) antibody
Verified DCX 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Doublecortin (DCX) (AA 1-360) antibody
DCX 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12 unconjugated

anti-Doublecortin (DCX) (AA 108-360) antibody
DCX 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Doublecortin (DCX) (AA 11-360) antibody
DCX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Doublecortin (DCX) (Ser30) antibody
DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Doublecortin (DCX) (pSer335) antibody
DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Doublecortin (DCX) antibody
DCX 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Doublecortin (DCX) antibody
DCX 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 3 e1 unconjugated

应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Evangelisti, Florian, Massimi, Dominici, Giannini, Galardi, Buè, Massalini, McDowell, Messi, Gulino, Farace, Ciafrè: "MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 12, pp. 4276-87, (2009) (PubMed).
抗原

Doublecortin (DCX)

别名

DCX

背景

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.

分子量

49.3 kDa

基因ID

1641

UniProt

O43602