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MATK 抗体

Cited in 1 publication. The 小鼠 单克隆 anti-MATK antibody (Clone 9D7) (ABIN969495) specifically detects MATK in WB, ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN969495
发货至: 中国
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Quick Overview for MATK 抗体 (ABIN969495)

抗原

See all MATK 抗体
MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

适用

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宿主

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小鼠

克隆类型

  • 58
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单克隆

标记

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This MATK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

9D7
  • 原理

    MATK Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human MATK expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • McShan, Zagozdzon, Park, Zrihan-Licht, Fu, Avraham, Avraham: "Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration." in: International journal of oncology, Vol. 21, Issue 1, pp. 197-205, (2002) (PubMed).

  • 抗原

    MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

    别名

    MATK

    背景

    MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

    分子量

    56 kDa

    基因ID

    4145

    UniProt

    P42679
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