This anti-alpha Fetoprotein antibody is a 小鼠 单克隆 antibody detecting alpha Fetoprotein in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Noda, Miyoshi, Kitada, Nakahara, Gao, Honke, Shiratori, Moriwaki, Sasaki, Kasahara, Hori, Hayashi, Taniguchi: "The enzymatic basis for the conversion of nonfucosylated to fucosylated alpha-fetoprotein by acyclic retinoid treatment in human hepatoma cells: activation of alpha1-6 fucosyltransferase." in: Tumour biology, Vol. 23, Issue 4, pp. 202-11, (2002) (PubMed).
Sayar, Yaniv, Goshen, Cohen: "Treatment of alpha-fetoprotein secreting hepatoblastoma by response of serum alpha-fetoprotein levels: a new concept." in: Pediatric hematology and oncology, Vol. 18, Issue 8, pp. 509-18, (2001) (PubMed).
抗原
alpha Fetoprotein (AFP)
(alpha-Fetoprotein (AFP))
别名
AFP
背景
AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.