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NK2 Homeobox 5 抗体

This anti-NK2 Homeobox 5 antibody is a 小鼠 单克隆 antibody detecting NK2 Homeobox 5 in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969487
发货至: 中国

Quick Overview for NK2 Homeobox 5 抗体 (ABIN969487)

抗原

See all NK2 Homeobox 5 (NKX2-5) 抗体
NK2 Homeobox 5 (NKX2-5)

适用

  • 41
  • 20
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 43
  • 7
  • 1
小鼠

克隆类型

  • 45
  • 6
单克隆

标记

  • 41
  • 3
  • 2
  • 2
  • 2
  • 1
This NK2 Homeobox 5 antibody is un-conjugated

应用范围

  • 44
  • 28
  • 8
  • 6
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
ELISA

克隆位点

2E1
  • 原理

    NKX2.5 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human NKX2.5 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Brewer, Alexandrovich, Mjaatvedt, Shah, Patient, Pizzey: "GATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesis." in: Stem cells and development, Vol. 14, Issue 4, pp. 425-39, (2005) (PubMed).

    Ikeda, Hiroi, Hosoda, Utsunomiya, Matsuo, Ito, Inoue, Sumiyoshi, Takano, Nagai, Komuro: "Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 66, Issue 6, pp. 561-3, (2002) (PubMed).

  • 抗原

    NK2 Homeobox 5 (NKX2-5)

    别名

    NKX2.5

    背景

    NKX2.5: NK2 transcription factor related, locus 5 (Drosophila), also known as CSX. It is a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

    分子量

    35 kDa

    基因ID

    1482

    UniProt

    P52952

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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