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Lipase A 抗体

This anti-Lipase A antibody is a 小鼠 单克隆 antibody detecting Lipase A in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969484
发货至: 中国

Quick Overview for Lipase A 抗体 (ABIN969484)

抗原

See all Lipase A (LIPA) 抗体
Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

适用

  • 31
  • 6
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  • 2
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宿主

  • 30
  • 5
小鼠

克隆类型

  • 31
  • 5
单克隆

标记

  • 24
  • 2
  • 2
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  • 1
  • 1
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This Lipase A antibody is un-conjugated

应用范围

  • 28
  • 13
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  • 7
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  • 3
  • 1
  • 1
ELISA

克隆位点

9G7F12
  • 原理

    LAL Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of LAL expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Drebber, Andersen, Kasper, Lohse, Stolte, Dienes: "Severe chronic diarrhea and weight loss in cholesteryl ester storage disease: a case report." in: World journal of gastroenterology : WJG, Vol. 11, Issue 15, pp. 2364-6, (2005) (PubMed).

    Boldrini, Devito, Biselli, Filocamo, Bosman: "Wolman disease and cholesteryl ester storage disease diagnosed by histological and ultrastructural examination of intestinal and liver biopsy." in: Pathology, research and practice, Vol. 200, Issue 3, pp. 231-40, (2004) (PubMed).

  • 抗原

    Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

    别名

    LAL

    背景

    Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.

    基因ID

    3988

    UniProt

    P38571
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