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WDR5 抗体

Cited in 2+ publications. This anti-WDR5 antibody is a 小鼠 单克隆 antibody detecting WDR5 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN969456
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for WDR5 抗体 (ABIN969456)

抗原

See all WDR5 抗体
WDR5 (WD Repeat Domain 5 (WDR5))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This WDR5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

7B11
  • 原理

    WDR5 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human WDR5 expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Patel, Vought, Dharmarajan, Cosgrove: "A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex." in: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32162-75, (2008) (PubMed).

    Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原

    WDR5 (WD Repeat Domain 5 (WDR5))

    别名

    WDR5

    背景

    WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.

    分子量

    36.6 kDa

    UniProt

    P61964
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