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TNNI2 抗体

This anti-TNNI2 antibody is a 小鼠 单克隆 antibody detecting TNNI2 in IHC, ELISA 和 FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969441
发货至: 中国

Quick Overview for TNNI2 抗体 (ABIN969441)

抗原

See all TNNI2 抗体
TNNI2 (Fast Skeletal Troponin I (TNNI2))

适用

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宿主

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小鼠

克隆类型

  • 34
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单克隆

标记

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This TNNI2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

2F12A11
  • 原理

    TNNI2 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human TNNI2 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

    Moran, Garriock, Miller, Heimark, Gregorio, Krieg: "Expression of the fast twitch troponin complex, fTnT, fTnI and fTnC, in vascular smooth muscle." in: Cell motility and the cytoskeleton, Vol. 65, Issue 8, pp. 652-61, (2008) (PubMed).

  • 抗原

    TNNI2 (Fast Skeletal Troponin I (TNNI2))

    别名

    TNNI2

    背景

    This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

    分子量

    21 kDa

    基因ID

    7136

    UniProt

    P48788
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