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Synaptophysin 抗体

This anti-Synaptophysin antibody (ABIN969428) is a Mouse Monoclonal antibody detecting Synaptophysin in WB, IHC, ELISA. Suitable for Human, Rat.
产品编号 ABIN969428
发货至: 中国

Quick Overview for Synaptophysin 抗体 (ABIN969428)

抗原

See all Synaptophysin (SYP) 抗体
Synaptophysin (SYP)

适用

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人, 大鼠

宿主

  • 64
  • 38
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  • 1
小鼠

克隆类型

  • 55
  • 51
单克隆

标记

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This Synaptophysin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

7H12
  • 原理

    SYP Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of SYP expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Gulubova, Vlaykova: "Chromogranin A-, serotonin-, synaptophysin- and vascular endothelial growth factor-positive endocrine cells and the prognosis of colorectal cancer: an immunohistochemical and ultrastructural study." in: Journal of gastroenterology and hepatology, Vol. 23, Issue 10, pp. 1574-85, (2009) (PubMed).

    Sterlacci, Fiegl, Hilbe, Auberger, Mikuz, Tzankov: "Clinical relevance of neuroendocrine differentiation in non-small cell lung cancer assessed by immunohistochemistry: a retrospective study on 405 surgically resected cases." in: Virchows Archiv : an international journal of pathology, Vol. 455, Issue 2, pp. 125-32, (2009) (PubMed).

    Xu, Dai, Xiang, Zhao, Ruan, Cheng, Zheng, Shu: "Nutritional factors in relation to endometrial cancer: a report from a population-based case-control study in Shanghai, China." in: International journal of cancer. Journal international du cancer, Vol. 120, Issue 8, pp. 1776-81, (2007) (PubMed).

  • 抗原

    Synaptophysin (SYP)

    别名

    SYP

    背景

    Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.

    分子量

    33.8 kDa

    基因ID

    6855

    UniProt

    P08247

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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