SPI1 抗体 (AA 124-271)
Quick Overview for SPI1 抗体 (AA 124-271) (ABIN969415)
抗原
See all SPI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 124-271
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原理
- SPI1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human SPI1 (AA: 124-271) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "PU.1 can regulate the ZNF300 promoter in APL-derived promyelocytes HL-60." in: Leukemia research, Vol. 34, Issue 12, pp. 1636-46, (2010) (PubMed).
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: "PU.1 can regulate the ZNF300 promoter in APL-derived promyelocytes HL-60." in: Leukemia research, Vol. 34, Issue 12, pp. 1636-46, (2010) (PubMed).
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- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
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别名
- SPI1
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背景
- This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 42 kDa
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基因ID
- 6688
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UniProt
- P17947
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途径
- Stem Cell Maintenance
抗原
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