电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SOX2 抗体

This anti-SOX2 antibody is a 小鼠 单克隆 antibody detecting SOX2 in ELISA, IHC 和 ICC. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN969414
发货至: 中国

Quick Overview for SOX2 抗体 (ABIN969414)

抗原

See all SOX2 抗体
SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

适用

  • 198
  • 95
  • 73
  • 21
  • 13
  • 11
  • 10
  • 10
  • 8
  • 8
  • 7
  • 7
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 165
  • 42
  • 2
小鼠

克隆类型

  • 162
  • 47
单克隆

标记

  • 112
  • 14
  • 10
  • 9
  • 6
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SOX2 antibody is un-conjugated

应用范围

  • 163
  • 98
  • 50
  • 45
  • 44
  • 40
  • 40
  • 29
  • 24
  • 22
  • 21
  • 16
  • 12
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

10F10
  • 原理

    SOX2 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human SOX2 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Dabdoub, Puligilla, Jones, Fritzsch, Cheah, Pevny, Kelley: "Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18396-401, (2008) (PubMed).

    Qin, Gan, Shao, Wang, Li, Wang, He, Xu, Zhang, Kou, Zeng, Sheng, Esteban, Gao, Pei: "Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33730-5, (2008) (PubMed).

    Tay, Zhang, Thomson, Lim, Rigoutsos: "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation." in: Nature, Vol. 455, Issue 7216, pp. 1124-8, (2008) (PubMed).

  • 抗原

    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

    别名

    SOX2

    背景

    This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

    分子量

    34 kDa

    基因ID

    6657

    UniProt

    P48431

    途径

    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
You are here:
Chat with us!