SOX2 抗体
Quick Overview for SOX2 抗体 (ABIN969414)
抗原
See all SOX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- SOX2 Antibody
-
纯化方法
- Ascitic fluid
-
免疫原
- Purified recombinant fragment of human SOX2 expressed in E. Coli.
-
亚型
- IgG1
-
-
-
-
应用备注
-
ELISA: 1/10000
ICC: 1/200 - 1/1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18396-401, (2008) (PubMed).
: "Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33730-5, (2008) (PubMed).
: "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation." in: Nature, Vol. 455, Issue 7216, pp. 1124-8, (2008) (PubMed).
: "
-
Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18396-401, (2008) (PubMed).
-
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
-
别名
- SOX2
-
背景
- This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
-
分子量
- 34 kDa
-
基因ID
- 6657
-
UniProt
- P48431
-
途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
抗原
-