SOX2 抗体 (AA 1-170)
Quick Overview for SOX2 抗体 (AA 1-170) (ABIN969413)
抗原
See all SOX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-170
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原理
- SOX2 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Reprogramming of human somatic cells to pluripotency with defined factors." in: Nature, Vol. 451, Issue 7175, pp. 141-6, (2008) (PubMed).
: "Sox-2 is expressed by glial and progenitor cells and Pax-6 is expressed by neuroblasts in the human subventricular zone." in: Experimental neurology, Vol. 204, Issue 2, pp. 828-31, (2007) (PubMed).
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: "Reprogramming of human somatic cells to pluripotency with defined factors." in: Nature, Vol. 451, Issue 7175, pp. 141-6, (2008) (PubMed).
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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别名
- SOX2
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背景
- SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
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分子量
- 34.3 kDa
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基因ID
- 6657
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UniProt
- P48431
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途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
抗原
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