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SMAD5 抗体

There are 2+ publications for this product available. The 小鼠 单克隆 anti-SMAD5 antibody is suitable to detect SMAD5 in samples from 人 和 大鼠. It has been validated for WB, ELISA, IHC, ICC 和 FACS.
产品编号 ABIN969404
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SMAD5 抗体 (ABIN969404)

抗原

See all SMAD5 抗体
SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

适用

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人, 大鼠

宿主

  • 127
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小鼠

克隆类型

  • 78
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单克隆

标记

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This SMAD5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

3H9
  • 原理

    SMAD5 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human SMAD5 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Chang, Chang, Lee, Lee, Yeh, Yeh, Cheng, Chien, Chiu: "Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3927-32, (2008) (PubMed).

    Monzen, Ito, Naito, Kasai, Hiroi, Hayashi, Shiojima, Yamazaki, Miyazono, Asashima, Nagai, Komuro: "A crucial role of a high mobility group protein HMGA2 in cardiogenesis." in: Nature cell biology, Vol. 10, Issue 5, pp. 567-74, (2008) (PubMed).

  • 抗原

    SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

    别名

    SMAD5

    背景

    Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo, lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.

    分子量

    52 kDa

    UniProt

    Q99717
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