RUNX1 抗体
Quick Overview for RUNX1 抗体 (ABIN969390)
抗原
See all RUNX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- RUNX1 Antibody
-
纯化方法
- Ascitic fluid
-
免疫原
- Synthesized peptide of human RUNX1.
-
亚型
- IgG1
-
-
-
-
应用备注
- ELISA: 1/10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis." in: Journal of virology, Vol. 82, Issue 13, pp. 6395-408, (2008) (PubMed).
: "AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4402-8, (2008) (PubMed).
-
: "RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis." in: Journal of virology, Vol. 82, Issue 13, pp. 6395-408, (2008) (PubMed).
-
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
-
别名
- RUNX1
-
背景
- Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
-
分子量
- 55 kDa
-
基因ID
- 861
-
UniProt
- Q01196
抗原
-