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RUNX1 抗体

Cited in 1 publication. This 小鼠 单克隆 anti-RUNX1 antibody (Clone 5A1) specifically detects RUNX1 in WB, ELISA 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN969389
发货至: 中国
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Quick Overview for RUNX1 抗体 (ABIN969389)

抗原

See all RUNX1 抗体
RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This RUNX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

克隆位点

5A1
  • 原理

    RUNX1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Synthesized peptide of human RUNX1.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Zharlyganova, Harada, Harada, Shinkarev, Zhumadilov, Zhunusova, Tchaizhunusova, Apsalikov, Kemaikin, Zhumadilov, Kawano, Kimura, Hoshi: "High frequency of AML1/RUNX1 point mutations in radiation-associated myelodysplastic syndrome around Semipalatinsk nuclear test site." in: Journal of radiation research, Vol. 49, Issue 5, pp. 549-55, (2008) (PubMed).

  • 抗原

    RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

    别名

    RUNX1

    背景

    Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

    分子量

    55 kDa

    基因ID

    861

    UniProt

    Q01196
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