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Reticulon 3 抗体

This anti-Reticulon 3 antibody is a 小鼠 单克隆 antibody detecting Reticulon 3 in ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN969387
发货至: 中国

Quick Overview for Reticulon 3 抗体 (ABIN969387)

抗原

See all Reticulon 3 (RTN3) 抗体
Reticulon 3 (RTN3)

适用

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  • 4
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宿主

  • 11
  • 4
小鼠

克隆类型

  • 13
  • 2
单克隆

标记

  • 15
This Reticulon 3 antibody is un-conjugated

应用范围

  • 12
  • 6
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  • 1
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ELISA, Immunohistochemistry (IHC)

克隆位点

10A8
  • 原理

    RTN3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of RTN3 expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Kim, Chai, Ryu: "Selenoprotein W as molecular target of methylmercury in human neuronal cells is down-regulated by GSH depletion." in: Biochemical and biophysical research communications, Vol. 330, Issue 4, pp. 1095-102, (2005) (PubMed).

    Cai, Saiyin, Lin, Zhang, Tang, Pan, Yu: "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain." in: Brain research. Molecular brain research, Vol. 138, Issue 2, pp. 236-43, (2005) (PubMed).

    Wakana, Koyama, Nakajima, Hatsuzawa, Nagahama, Tani, Hauri, Melançon, Tagaya: "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi." in: Biochemical and biophysical research communications, Vol. 334, Issue 4, pp. 1198-205, (2005) (PubMed).

    Oertle, Klinger, Stuermer, Schwab: "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 10, pp. 1238-47, (2003) (PubMed).

  • 抗原

    Reticulon 3 (RTN3)

    别名

    RTN3

    背景

    RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.

    分子量

    113 kDa

    UniProt

    O95197
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