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PSIP1 抗体

This anti-PSIP1 antibody is a 小鼠 单克隆 antibody detecting PSIP1 in WB, IHC, ELISA 和 ICC. Suitable for 人, 大鼠 和 猴. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN969370
发货至: 中国

Quick Overview for PSIP1 抗体 (ABIN969370)

抗原

See all PSIP1 抗体
PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

适用

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人, 大鼠, 猴

宿主

  • 21
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小鼠

克隆类型

  • 20
  • 14
单克隆

标记

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This PSIP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

克隆位点

6E4
  • 原理

    PSIP1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human PSIP1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shun, Botbol, Li, Di Nunzio, Daigle, Yan, Lieberman, Lavigne, Engelman: "Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity." in: Journal of virology, Vol. 82, Issue 23, pp. 11555-67, (2008) (PubMed).

  • 抗原

    PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

    别名

    PSIP1

    背景

    Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.

    分子量

    75 kDa

    基因ID

    11168

    UniProt

    O75475

    途径

    Chromatin Binding, Ribonucleoprotein Complex Subunit Organization
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