电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Progesterone Receptor 抗体 (AA 730-871)

PGR 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8A11H1 unconjugated
产品编号 ABIN969352
发货至: 中国
  • 抗原 See all Progesterone Receptor (PGR) 抗体
    Progesterone Receptor (PGR)
    抗原表位
    • 16
    • 16
    • 15
    • 11
    • 10
    • 10
    • 9
    • 8
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 730-871
    适用
    • 207
    • 40
    • 37
    • 16
    • 15
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 147
    • 64
    • 1
    小鼠
    克隆类型
    • 141
    • 70
    • 1
    单克隆
    标记
    • 126
    • 15
    • 10
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Progesterone Receptor antibody is un-conjugated
    应用范围
    • 173
    • 83
    • 58
    • 33
    • 29
    • 26
    • 26
    • 23
    • 18
    • 18
    • 17
    • 11
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    原理
    PGR Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of PGR (aa730-871) expressed in E. Coli.
    克隆位点
    8A11H1
    亚型
    IgG1
    Top Product
    Discover our top product PGR Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • LEplattenier, Lai, van den Ham, Mol, van Sluijs, Teske: "Regulation of COX-2 expression in canine prostate carcinoma: increased COX-2 expression is not related to inflammation." in: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, Vol. 21, Issue 4, pp. 776-82, (2007) (PubMed).

    Yin, Lin, Cheng, Marsh, Utsunomiya, Ishikawa, Xue, Reierstad, Innes, Thung, Kim, Xu, Bulun: "Progesterone receptor regulates Bcl-2 gene expression through direct binding to its promoter region in uterine leiomyoma cells." in: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 11, pp. 4459-66, (2007) (PubMed).

    Saito, Ito, Nagase, Suzuki, Akahira, Okamura, Yaegashi, Sasano: "Progesterone receptor isoforms as a prognostic marker in human endometrial carcinoma." in: Cancer science, Vol. 97, Issue 12, pp. 1308-14, (2006) (PubMed).

    Tung, Abdel-Hafiz, Shen, Harvell, Nitao, Richer, Sartorius, Takimoto, Horwitz: "Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2656-70, (2006) (PubMed).

    Buser, Gass-Handel, Wyszomierski, Doppler, Leonhardt, Schaack, Rosen, Watkin, Anderson, Edwards: "Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 1, pp. 106-25, (2006) (PubMed).

  • 抗原
    Progesterone Receptor (PGR)
    别名
    PGR (PGR 产品)
    背景

    Description: PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.

    Aliases: PR, NR3C3, PGR

    基因ID
    5241
    HGNC
    5241
    UniProt
    P06401
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
You are here:
客服