PEG10 抗体 (AA 1-120)
(3 references)Quick Overview for PEG10 抗体 (AA 1-120) (ABIN969348)
抗原
See all PEG10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-120
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原理
- PEG10 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of PEG10 (aa1-120) expressed in E. Coli.
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亚型
- IgG1
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anti-Paternally Expressed 10 (PEG10) (AA 1-325) antibody
PEG10 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paternally Expressed 10 (PEG10) (AA 1-325) antibodyPEG10 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Paternally Expressed 10 (PEG10) antibodyPEG10 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Paternally Expressed 10 (PEG10) (AA 1-30), (N-Term) antibodyPEG10 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB31292 unconjugated
anti-Paternally Expressed 10 (PEG10) (AA 1-30), (N-Term) antibodyPEG10 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "uORFs, reinitiation and alternative translation start sites in human mRNAs." in: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).
: "PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma." in: FEBS letters, Vol. 582, Issue 18, pp. 2793-8, (2008) (PubMed).
: "Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells." in: Oncogene, Vol. 26, Issue 39, pp. 5741-51, (2007) (PubMed).
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: "uORFs, reinitiation and alternative translation start sites in human mRNAs." in: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).
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- PEG10 (Paternally Expressed 10 (PEG10))
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别名
- PEG10
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背景
- PEG10: paternally expressed 10. This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.
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UniProt
- Q86TG7
抗原
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