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NCOR1 抗体 (AA 1-192)

This anti-NCOR1 antibody (ABIN969310) is a Mouse Monoclonal antibody detecting NCOR1 in ELISA, IHC. Suitable for Human.
产品编号 ABIN969310
发货至: 中国

Quick Overview for NCOR1 抗体 (AA 1-192) (ABIN969310)

抗原

See all NCOR1 抗体
NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

适用

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宿主

  • 52
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小鼠

克隆类型

  • 57
  • 1
单克隆

标记

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This NCOR1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)

克隆位点

7A7A9
  • 抗原表位

    • 15
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    • 1
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    AA 1-192

    原理

    NCOR1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Atsumi, Tomita, Kiyoi, Naoe: "Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo." in: Biochemical and biophysical research communications, Vol. 345, Issue 4, pp. 1471-80, (2006) (PubMed).

    Zhang, Yoon, Wong: "JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6404-14, (2005) (PubMed).

  • 抗原

    NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

    别名

    NCOR1

    背景

    NCOR1: Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

    基因ID

    9611

    UniProt

    O75376

    途径

    Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
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