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NCOA3 抗体 (AA 1-200)

Cited in 2+ publications. The 小鼠 单克隆 anti-NCOA3 antibody (Clone 2C11B12) (ABIN969309) specifically detects NCOA3 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN969309
发货至: 中国
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Quick Overview for NCOA3 抗体 (AA 1-200) (ABIN969309)

抗原

See all NCOA3 抗体
NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NCOA3 antibody is un-conjugated

应用范围

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ELISA

克隆位点

2C11B12
  • 抗原表位

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    AA 1-200

    原理

    NCOA3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of NCOA3 (aa1-200) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Rangel, Torabian, Shaikh, Nosrati, Baehner, Haqq, Leong, Miller, Sagebiel, Kashani-Sabet: "Prognostic significance of nuclear receptor coactivator-3 overexpression in primary cutaneous melanoma." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 24, Issue 28, pp. 4565-9, (2006) (PubMed).

    Zheng, Wu, Smith, OMalley: "Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor." in: Molecular and cellular biology, Vol. 25, Issue 18, pp. 8273-84, (2005) (PubMed).

  • 抗原

    NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

    别名

    NCOA3

    背景

    NCOA3: nuclear receptor coactivator 3. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

    UniProt

    Q9Y6Q9

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha
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