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MYL3/CMLC1 抗体

This anti-MYL3/CMLC1 antibody is a 小鼠 单克隆 antibody detecting MYL3/CMLC1 in WB, IHC 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969303

Quick Overview for MYL3/CMLC1 抗体 (ABIN969303)

抗原

See all MYL3/CMLC1 (MYL3) 抗体
MYL3/CMLC1 (MYL3) (Myosin, Light Chain 3 (MYL3))

适用

  • 41
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  • 1
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宿主

  • 39
  • 5
小鼠

克隆类型

  • 40
  • 3
单克隆

标记

  • 32
  • 2
  • 1
  • 1
  • 1
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This MYL3/CMLC1 antibody is un-conjugated

应用范围

  • 36
  • 22
  • 19
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  • 3
  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

3F8
  • 原理

    MYL3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of MYL3 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Haase, Dobbernack, Tünnemann, Karczewski, Cardoso, Petzhold, Schlegel, Lutter, Pierschalek, Behlke, Morano: "Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 7, pp. 865-73, (2006) (PubMed).

    Xie, Huang, Huang, Zhou, Gong: "The functional domains of human ventricular myosin light chain 1." in: Biophysical chemistry, Vol. 106, Issue 1, pp. 57-66, (2003) (PubMed).

  • 抗原

    MYL3/CMLC1 (MYL3) (Myosin, Light Chain 3 (MYL3))

    别名

    MYL3

    背景

    Myosins are a large superfamily of motor proteins that move along actin filaments, while hydrolyzing ATP. Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains and four light chains. Activation of smooth and cardiac muscle primarily involves pathways which increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Human myosin light chain has clinical application as a cardiac marker. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.

    分子量

    22 kDa

    基因ID

    4634

    UniProt

    P08590
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