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LSD1 抗体

KDM1A 适用: 人, 小鼠, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1B2E5 unconjugated
产品编号 ABIN969264
发货至: 中国
  • 抗原 See all LSD1 (KDM1A) 抗体
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    适用
    • 74
    • 36
    • 29
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 猴
    宿主
    • 58
    • 14
    • 1
    小鼠
    克隆类型
    • 58
    • 16
    单克隆
    标记
    • 54
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LSD1 antibody is un-conjugated
    应用范围
    • 66
    • 34
    • 25
    • 21
    • 17
    • 13
    • 13
    • 10
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    原理
    LSD1/AOF2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human LSD1 expressed in E. Coli.
    克隆位点
    1B2E5
    亚型
    IgG1
    Top Product
    Discover our top product KDM1A Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shi, Matson, Lan, Iwase, Baba, Shi: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).

    Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).

  • 抗原
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    别名
    LSD1/AOF2 (KDM1A 产品)
    背景
    The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
    分子量
    93 kDa
    UniProt
    O60341
    途径
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect
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