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KLHL22 抗体

This 小鼠 单克隆 antibody specifically detects KLHL22 in WB, ELISA 和 ICC. It exhibits reactivity toward 人.
产品编号 ABIN969247
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KLHL22 抗体 (ABIN969247)

抗原

See all KLHL22 抗体
KLHL22 (Kelch-Like 22 (KLHL22))

适用

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宿主

  • 36
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小鼠

克隆类型

  • 37
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单克隆

标记

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This KLHL22 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

克隆位点

7B10
  • 原理

    KLHL22 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human KLHL22 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    KLHL22 (Kelch-Like 22 (KLHL22))

    别名

    KLHL22

    背景

    KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophilakelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.

    分子量

    72 kDa

    基因ID

    84861

    UniProt

    Q53GT1
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