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KARS 抗体 (AA 90-174)

This 小鼠 单克隆 antibody specifically detects KARS in IHC 和 ELISA. It exhibits reactivity toward 人. It has been mentioned in 4+ publications
产品编号 ABIN969226
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KARS 抗体 (AA 90-174) (ABIN969226)

抗原

See all KARS 抗体
KARS (Lysyl-tRNA Synthetase (KARS))

适用

  • 65
  • 27
  • 23
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 64
  • 3
小鼠

克隆类型

  • 46
  • 22
单克隆

标记

  • 28
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This KARS antibody is un-conjugated

应用范围

  • 47
  • 21
  • 15
  • 15
  • 14
  • 14
  • 13
  • 13
  • 8
  • 4
  • 3
  • 1
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Immunohistochemistry (IHC), ELISA

克隆位点

8G12C1
  • 抗原表位

    • 15
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 90-174

    原理

    KARS Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of KARS(aa90-174) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Sampath, Mazumder, Seshadri, Gerber, Chavatte, Kinter, Ting, Dignam, Kim, Driscoll, Fox: "Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation." in: Cell, Vol. 119, Issue 2, pp. 195-208, (2004) (PubMed).

    Sang Lee, Gyu Park, Park, Seol, Lee, Kim: "Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex." in: Biochemical and biophysical research communications, Vol. 291, Issue 1, pp. 158-64, (2002) (PubMed).

    Cen, Khorchid, Javanbakht, Gabor, Stello, Shiba, Musier-Forsyth, Kleiman: "Incorporation of lysyl-tRNA synthetase into human immunodeficiency virus type 1." in: Journal of virology, Vol. 75, Issue 11, pp. 5043-8, (2001) (PubMed).

    Tolkunova, Park, Xia, King, Davidson: "The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35063-9, (2000) (PubMed).

  • 抗原

    KARS (Lysyl-tRNA Synthetase (KARS))

    别名

    KARS

    背景

    KARS: lysyl-tRNA synthetase. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.

    基因ID

    3735

    UniProt

    Q15046
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