IL-2 抗体
Quick Overview for IL-2 抗体 (ABIN969214)
抗原
See all IL-2 (IL2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- IL-2 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of IL2 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "TGF-beta inhibits IL-2 production and promotes cell cycle arrest in TCR-activated effector/memory T cells in the presence of sustained TCR signal transduction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1490-8, (2008) (PubMed).
: "Regulation of IL-2 expression by transcription factor BACH2 in umbilical cord blood CD4+ T cells." in: Leukemia, Vol. 22, Issue 12, pp. 2201-7, (2008) (PubMed).
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: "TGF-beta inhibits IL-2 production and promotes cell cycle arrest in TCR-activated effector/memory T cells in the presence of sustained TCR signal transduction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1490-8, (2008) (PubMed).
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- IL-2 (IL2) (Interleukin 2 (IL2))
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别名
- IL-2
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背景
- IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6 kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
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分子量
- 17.6 kDa
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基因ID
- 3558
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UniProt
- P60568
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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