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IL-2 抗体

This anti-IL-2 antibody is a 小鼠 单克隆 antibody detecting IL-2 in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969214
发货至: 中国

Quick Overview for IL-2 抗体 (ABIN969214)

抗原

See all IL-2 (IL2) 抗体
IL-2 (IL2) (Interleukin 2 (IL2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-2 antibody is un-conjugated

应用范围

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ELISA

克隆位点

8D5
  • 原理

    IL-2 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of IL2 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Das, Levine: "TGF-beta inhibits IL-2 production and promotes cell cycle arrest in TCR-activated effector/memory T cells in the presence of sustained TCR signal transduction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1490-8, (2008) (PubMed).

    Lesniewski, Haviernik, Weitzel, Kadereit, Kozik, Fanning, Yang, Hegerfeldt, Finney, Ratajczak, Greco, Paul, Maciejewski, Laughlin: "Regulation of IL-2 expression by transcription factor BACH2 in umbilical cord blood CD4+ T cells." in: Leukemia, Vol. 22, Issue 12, pp. 2201-7, (2008) (PubMed).

  • 抗原

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    IL-2

    背景

    IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6 kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

    分子量

    17.6 kDa

    基因ID

    3558

    UniProt

    P60568

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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