Hexokinase 2 抗体
(3 references)Quick Overview for Hexokinase 2 抗体 (ABIN969196)
抗原
See all Hexokinase 2 (HK2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HK2 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human HK2 expressed in E. Coli.
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亚型
- IgG1
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anti-Hexokinase 2 (HK2) (AA 1-120) antibody
HK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Hexokinase 2 (HK2) (AA 818-917) antibodyHK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H1 unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (C-Term) antibodyHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人 WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Hexokinase 2 (HK2) (AA 469-669) antibodyHK2 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (AA 453-483) antibodyHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5333 unconjugated
anti-Hexokinase 2 (HK2) (AA 334-526) antibodyHK2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (AA 1-170) antibodyHK2 适用: 人 WB 宿主: 小鼠 Monoclonal 1798CT748-15-25 unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Real-time quantitative RT-PCR assessment of PIM-1 and hK2 mRNA expression in benign prostate hyperplasia and prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 26, Issue 3, pp. 303-8, (2009) (PubMed).
: "Expression of glucose transporters and hexokinase II in cholangiocellular carcinoma compared using [18F]-2-fluro-2-deoxy-D-glucose positron emission tomography." in: Cancer science, Vol. 99, Issue 2, pp. 260-6, (2008) (PubMed).
: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, (2006) (PubMed).
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: "Real-time quantitative RT-PCR assessment of PIM-1 and hK2 mRNA expression in benign prostate hyperplasia and prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 26, Issue 3, pp. 303-8, (2009) (PubMed).
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- Hexokinase 2 (HK2)
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别名
- HK2
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背景
- The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases .Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
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分子量
- 102 kDa
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UniProt
- P52789
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途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
抗原
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