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HDAC4 抗体

This anti-HDAC4 antibody is a 小鼠 单克隆 antibody detecting HDAC4 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN969190
发货至: 中国

Quick Overview for HDAC4 抗体 (ABIN969190)

抗原

See all HDAC4 抗体
HDAC4 (Histone Deacetylase 4 (HDAC4))

适用

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宿主

  • 110
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  • 1
小鼠

克隆类型

  • 107
  • 18
单克隆

标记

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This HDAC4 antibody is un-conjugated

应用范围

  • 86
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Western Blotting (WB), ELISA

克隆位点

7B2
  • 原理

    HDAC4 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human HDAC4 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS containing 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shao, Li, Zhang, Liu, Liu, Zhao, Shen, Li: "Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX." in: Nucleic acids research, Vol. 38, Issue 9, pp. 2813-24, (2010) (PubMed).

    Ficner: "Novel structural insights into class I and II histone deacetylases." in: Current topics in medicinal chemistry, Vol. 9, Issue 3, pp. 235-40, (2009) (PubMed).

    Nishino, Miyazaki, Hoshino, Miwa, Horinouchi, Yoshida: "14-3-3 regulates the nuclear import of class IIa histone deacetylases." in: Biochemical and biophysical research communications, Vol. 377, Issue 3, pp. 852-6, (2008) (PubMed).

  • 抗原

    HDAC4 (Histone Deacetylase 4 (HDAC4))

    别名

    HDAC4

    背景

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

    分子量

    119 kDa

    基因ID

    9759

    UniProt

    P56524

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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