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HDAC3 抗体 (AA 224-428)

HDAC3 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7G6C5 unconjugated
产品编号 ABIN969188
发货至: 中国
  • 抗原 See all HDAC3 抗体
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    抗原表位
    • 16
    • 15
    • 15
    • 11
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 224-428
    适用
    • 116
    • 71
    • 68
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 92
    • 23
    • 1
    小鼠
    克隆类型
    • 90
    • 26
    单克隆
    标记
    • 62
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HDAC3 antibody is un-conjugated
    应用范围
    • 89
    • 47
    • 36
    • 26
    • 25
    • 24
    • 16
    • 16
    • 14
    • 9
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    原理
    HDAC3 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli.
    克隆位点
    7G6C5
    亚型
    IgG2a
    Top Product
    Discover our top product HDAC3 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Spurling, Godman, Noonan, Rasmussen, Rosenberg, Giardina: "HDAC3 overexpression and colon cancer cell proliferation and differentiation." in: Molecular carcinogenesis, Vol. 47, Issue 2, pp. 137-47, (2008) (PubMed).

    Grégoire, Xiao, Nie, Zhang, Xu, Li, Wong, Seto, Yang: "Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2." in: Molecular and cellular biology, Vol. 27, Issue 4, pp. 1280-95, (2007) (PubMed).

    Libý, Kostrouchová, Pohludka, Yilma, Hrabal, Sikora, Brozová, Kostrouchová, Rall, Kostrouch: "Elevated and deregulated expression of HDAC3 in human astrocytic glial tumours." in: Folia biologica, Vol. 52, Issue 1-2, pp. 21-33, (2006) (PubMed).

  • 抗原
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    别名
    HDAC3 (HDAC3 产品)
    背景
    HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
    分子量
    48.8 kDa
    基因ID
    8841
    UniProt
    O15379
    途径
    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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