Glutamate Receptor 3 抗体
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北京 101111
Quick Overview for Glutamate Receptor 3 抗体 (ABIN969177)
抗原
See all Glutamate Receptor 3 (GRIA3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GRIA3 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human GRIA3 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "A population-based association study of candidate genes for depression and sleep disturbance." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 2, pp. 468-76, (2010) (PubMed).
: "Aberrant GRIA3 transcripts with multi-exon duplications in a family with X-linked mental retardation." in: American journal of medical genetics. Part A, Vol. 149A, Issue 6, pp. 1280-9, (2009) (PubMed).
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: "A population-based association study of candidate genes for depression and sleep disturbance." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 2, pp. 468-76, (2010) (PubMed).
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- Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
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别名
- GRIA3
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背景
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
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分子量
- 101 kDa
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基因ID
- 2892
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UniProt
- P42263
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途径
- PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane
抗原
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