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Glutamate Receptor 3 抗体

Cited in 2+ publications. This 小鼠 单克隆 anti-Glutamate Receptor 3 antibody (Clone 1D2) specifically detects Glutamate Receptor 3 in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN969177
发货至: 中国
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Quick Overview for Glutamate Receptor 3 抗体 (ABIN969177)

抗原

See all Glutamate Receptor 3 (GRIA3) 抗体
Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

适用

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宿主

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小鼠

克隆类型

  • 57
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单克隆

标记

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This Glutamate Receptor 3 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)

克隆位点

1D2
  • 原理

    GRIA3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human GRIA3 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Utge, Soronen, Partonen, Loukola, Kronholm, Pirkola, Nyman, Porkka-Heiskanen, Paunio: "A population-based association study of candidate genes for depression and sleep disturbance." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 2, pp. 468-76, (2010) (PubMed).

    Bonnet, Leheup, Béri, Philippe, Grégoire, Jonveaux: "Aberrant GRIA3 transcripts with multi-exon duplications in a family with X-linked mental retardation." in: American journal of medical genetics. Part A, Vol. 149A, Issue 6, pp. 1280-9, (2009) (PubMed).

  • 抗原

    Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

    别名

    GRIA3

    背景

    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

    分子量

    101 kDa

    基因ID

    2892

    UniProt

    P42263

    途径

    PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane
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