GPI 抗体
(3 references)Quick Overview for GPI 抗体 (ABIN969176)
抗原
See all GPI 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Glucose-6-phosphate isomerase Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human GPI expressed in E. Coli.
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亚型
- IgG1
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anti-Glucose-6-Phosphate Isomerase (GPI) (AA 2-554) antibody
GPI 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucose-6-Phosphate Isomerase (GPI) (AA 81-93) antibodyVerified GPI 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Glucose-6-Phosphate Isomerase (GPI) (AA 1-558) antibodyGPI 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glucose-6-Phosphate Isomerase (GPI) antibodyGPI 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal CPTC-GPI-1 unconjugated
anti-Glucose-6-Phosphate Isomerase (GPI) (AA 1-558) antibodyGPI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8B8 unconjugated
anti-Glucose-6-Phosphate Isomerase (GPI) (AA 1-558) antibodyGPI 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glucose-6-Phosphate Isomerase (GPI) (AA 335-558) antibodyGPI 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucose-6-Phosphate Isomerase (GPI) antibodyGPI 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucose-6-Phosphate Isomerase (GPI) (C-Term) antibodyGPI 适用: 人, 犬, 猴, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucose-6-Phosphate Isomerase (GPI) antibodyGPI 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Patients with inflammatory arthritic diseases harbor elevated serum and synovial fluid levels of free and immune-complexed glucose-6-phosphate isomerase (G6PI)." in: Biochemical and biophysical research communications, Vol. 349, Issue 2, pp. 838-45, (2006) (PubMed).
: "AMF/G6PI induces differentiation of leukemic cells via an unknown receptor that differs from gp78." in: Leukemia & lymphoma, Vol. 47, Issue 10, pp. 2234-43, (2006) (PubMed).
: "Glucose-6-phosphate isomerase variants play a key role in the generation of anti-GPI antibodies: possible mechanism of autoantibody production." in: Biochemical and biophysical research communications, Vol. 323, Issue 2, pp. 518-22, (2004) (PubMed).
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: "Patients with inflammatory arthritic diseases harbor elevated serum and synovial fluid levels of free and immune-complexed glucose-6-phosphate isomerase (G6PI)." in: Biochemical and biophysical research communications, Vol. 349, Issue 2, pp. 838-45, (2006) (PubMed).
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- GPI (Glucose-6-Phosphate Isomerase (GPI))
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别名
- Glucose-6-phosphate isomerase
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物质类
- Viral Protein
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背景
- Glucose-6-phosphate isomerase, or phosphoglucose isomerase, also known as GPI. It belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
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分子量
- 63 kDa
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基因ID
- 2821
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UniProt
- P06744
抗原
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