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GATA3 抗体

This anti-GATA3 antibody is a 小鼠 单克隆 antibody detecting GATA3 in ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969168
发货至: 中国

Quick Overview for GATA3 抗体 (ABIN969168)

抗原

See all GATA3 抗体
GATA3 (GATA Binding Protein 3 (GATA3))

适用

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宿主

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小鼠

克隆类型

  • 117
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单克隆

标记

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This GATA3 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)

克隆位点

7B5
  • 原理

    GATA3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human GATA3 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Muzzioli, Stecconi, Moresi, Provinciali: "Zinc improves the development of human CD34+ cell progenitors towards NK cells and increases the expression of GATA-3 transcription factor in young and old ages." in: Biogerontology, Vol. 10, Issue 5, pp. 593-604, (2009) (PubMed).

    van Hamburg, Mus, de Bruijn, de Vogel, Boon, Cornelissen, Asmawidjaja, Hendriks, Lubberts: "GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis." in: Arthritis and rheumatism, Vol. 60, Issue 3, pp. 750-9, (2009) (PubMed).

  • 抗原

    GATA3 (GATA Binding Protein 3 (GATA3))

    别名

    GATA3

    背景

    This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. (provided by RefSeq) Tissue specificity: T-cells and endothelial cells RD: GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.

    分子量

    48 kDa

    基因ID

    2625

    UniProt

    P23771

    途径

    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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