电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

GATA3 抗体 (AA 175-388)

There are 4+ publications for this product available. The 小鼠 单克隆 anti-GATA3 antibody is suitable to detect GATA3 in samples from 人. It has been validated for ELISA.
产品编号 ABIN969167
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GATA3 抗体 (AA 175-388) (ABIN969167)

抗原

See all GATA3 抗体
GATA3 (GATA Binding Protein 3 (GATA3))

适用

  • 176
  • 88
  • 19
  • 8
  • 7
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1

宿主

  • 136
  • 61
  • 2
  • 1
小鼠

克隆类型

  • 101
  • 99
单克隆

标记

  • 89
  • 11
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
This GATA3 antibody is un-conjugated

应用范围

  • 129
  • 68
  • 46
  • 32
  • 31
  • 28
  • 27
  • 26
  • 18
  • 11
  • 9
  • 7
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
ELISA

克隆位点

1A10D1
  • 抗原表位

    • 47
    • 34
    • 16
    • 15
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 175-388

    原理

    GATA3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of GATA3 (aa175-388) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Gulbinas, Berberat, Dambrauskas, Giese, Giese, Autschbach, Kleeff, Meuer, Büchler, Friess: "Aberrant gata-3 expression in human pancreatic cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 2, pp. 161-9, (2006) (PubMed).

    Erpenbeck, Hagenberg, Krentel, Discher, Braun, Hohlfeld, Krug: "Regulation of GATA-3, c-maf and T-bet mRNA expression in bronchoalveolar lavage cells and bronchial biopsies after segmental allergen challenge." in: International archives of allergy and immunology, Vol. 139, Issue 4, pp. 306-16, (2006) (PubMed).

    Mehra, Varambally, Ding, Shen, Sabel, Ghosh, Chinnaiyan, Kleer: "Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis." in: Cancer research, Vol. 65, Issue 24, pp. 11259-64, (2005) (PubMed).

    Jiang: "Development of a new biotic index to assess freshwater pollution." in: Environmental pollution (Barking, Essex : 1987), Vol. 139, Issue 2, pp. 306-17, (2005) (PubMed).

  • 抗原

    GATA3 (GATA Binding Protein 3 (GATA3))

    别名

    GATA3

    背景

    GATA3: GATA binding protein 3. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells, macrophages, or HeLa cell lines. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1,but no other structural homologies between the 2 genes could be found.

    基因ID

    2625

    UniProt

    P23771

    途径

    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
You are here: