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GATA3 抗体 (AA 175-388)

This anti-GATA3 antibody is a 小鼠 单克隆 antibody detecting GATA3 in ELISA. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN969167
发货至: 中国

Quick Overview for GATA3 抗体 (AA 175-388) (ABIN969167)

抗原

See all GATA3 抗体
GATA3 (GATA Binding Protein 3 (GATA3))

适用

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宿主

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小鼠

克隆类型

  • 117
  • 97
单克隆

标记

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This GATA3 antibody is un-conjugated

应用范围

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ELISA

克隆位点

1A10D1
  • 抗原表位

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    AA 175-388

    原理

    GATA3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of GATA3 (aa175-388) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Gulbinas, Berberat, Dambrauskas, Giese, Giese, Autschbach, Kleeff, Meuer, Büchler, Friess: "Aberrant gata-3 expression in human pancreatic cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 2, pp. 161-9, (2006) (PubMed).

    Erpenbeck, Hagenberg, Krentel, Discher, Braun, Hohlfeld, Krug: "Regulation of GATA-3, c-maf and T-bet mRNA expression in bronchoalveolar lavage cells and bronchial biopsies after segmental allergen challenge." in: International archives of allergy and immunology, Vol. 139, Issue 4, pp. 306-16, (2006) (PubMed).

    Mehra, Varambally, Ding, Shen, Sabel, Ghosh, Chinnaiyan, Kleer: "Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis." in: Cancer research, Vol. 65, Issue 24, pp. 11259-64, (2005) (PubMed).

    Jiang: "Development of a new biotic index to assess freshwater pollution." in: Environmental pollution (Barking, Essex : 1987), Vol. 139, Issue 2, pp. 306-17, (2005) (PubMed).

  • 抗原

    GATA3 (GATA Binding Protein 3 (GATA3))

    别名

    GATA3

    背景

    GATA3: GATA binding protein 3. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells, macrophages, or HeLa cell lines. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1,but no other structural homologies between the 2 genes could be found.

    基因ID

    2625

    UniProt

    P23771

    途径

    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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