电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

FOXD3 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-FOXD3 antibody is suitable to detect FOXD3 in samples from 人, 小鼠 和 猴. It has been validated for WB 和 ELISA.
产品编号 ABIN969152
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FOXD3 抗体 (ABIN969152)

抗原

See all FOXD3 抗体
FOXD3 (Forkhead Box D3 (FOXD3))

适用

  • 37
  • 30
  • 5
  • 2
  • 2
  • 2
  • 2
人, 小鼠, 猴

宿主

  • 35
  • 2
  • 1
  • 1
小鼠

克隆类型

  • 37
  • 2
单克隆

标记

  • 15
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FOXD3 antibody is un-conjugated

应用范围

  • 15
  • 13
  • 13
  • 13
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA

克隆位点

5G9
  • 原理

    FOXD3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human FOXD3 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Saleem, Banerjee-Basu, Berry, Baxevanis, Walter: "Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1." in: American journal of human genetics, Vol. 68, Issue 3, pp. 627-41, (2001) (PubMed).

  • 抗原

    FOXD3 (Forkhead Box D3 (FOXD3))

    别名

    FOXD3

    背景

    FoxD3 is a member of the Forkhead Box family and is characterized by a winged-helix DNA-binding structure and the important role it plays in embryonic development . This transcriptional regulator is required for the maintenance of pluripotency in the pre-implantation and peri-implantation stages of mouse embryonic development and is also required for trophoblast formation . FoxD3 is required for the maintenance of the mammalian neural crest, FoxD3(-/-) mouse embryos fail around the time of implantation with loss of neural crest-derived structures . FoxD3 also forms a regulatory network with Oct-4 and NANOG to maintain the pluripotency of ES cells .Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis .Tissue specificity: Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined .

    分子量

    48 kDa

    UniProt

    Q9UJU5
You are here: