This anti-Fibrinogen beta Chain antibody is a 小鼠 单克隆 antibody detecting Fibrinogen beta Chain in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Koch, Hoppmann, Biele, Mueller, Schömig, Kastrati: "Fibrinogen genes and myocardial infarction: a haplotype analysis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 4, pp. 758-63, (2008) (PubMed).
Vu, Bolton-Maggs, Parr, Morris, de Moerloose, Neerman-Arbez: "Congenital afibrinogenemia: identification and expression of a missense mutation in FGB impairing fibrinogen secretion." in: Blood, Vol. 102, Issue 13, pp. 4413-5, (2003) (PubMed).
抗原
Fibrinogen beta Chain (FGB)
别名
FGB
背景
Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.