FES 抗体 (AA 613-822)
(3 references)Quick Overview for FES 抗体 (AA 613-822) (ABIN969134)
抗原
See all FES 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 613-822
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原理
- FES Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of FES (AA:613-822)expressed in E. Coli.
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亚型
- IgG1
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anti-Feline Sarcoma Oncogene (FES) antibody
FES 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 7C7 unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 120-420) antibodyFES 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 1-822) antibodyFES 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A3-1E5 unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 1-822) antibodyFES 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (C-Term) antibodyFES 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 510-770) antibodyFES 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 121-220) antibodyFES 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (Internal Region) antibodyFES 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 28-77) antibodyFES 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow, Pig, 猴, 马, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 146-195) antibodyFES 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Pig, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer." in: The Journal of biological chemistry, Vol. 281, Issue 13, pp. 8829-35, (2006) (PubMed).
: "Design and simulation of a pneumatic, stored-energy, hybrid orthosis for gait restoration." in: Journal of biomechanical engineering, Vol. 127, Issue 6, pp. 1014-9, (2006) (PubMed).
: "Functional electrostimulation of muscles as a method for restoring motor functions." in: Neuroscience and behavioral physiology, Vol. 35, Issue 7, pp. 709-14, (2006) (PubMed).
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: "A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer." in: The Journal of biological chemistry, Vol. 281, Issue 13, pp. 8829-35, (2006) (PubMed).
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- FES (Feline Sarcoma Oncogene (FES))
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别名
- FES
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背景
- FES (feline sarcoma oncogene) and Fer are the only two members of a unique family of cytoplasmic protein tyrosine kinases. FES and Fer contain a central Src homology-2 (SH2) domain and a carboxy-terminal tyrosine kinase catalytic domain. They are structurally distinguished from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of amino-terminal Fer/CIP4 homology and coiled-coil domains. FES was originally identified as an oncogene from avian and feline retroviruses. Human c-Fes has been implicated in myeloid, vascular endothelial and neuronal cell differentiation. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Mutations may activate the FES kinase and thereby contribute to cancer. However, recent data strongly suggests that the c-FES protein-tyrosine kinase is a tumor suppressor rather than a dominant oncogene in colorectal cancer.
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基因ID
- 2242
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UniProt
- P07332
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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