ETV1 抗体 (AA 1-191)
Quick Overview for ETV1 抗体 (AA 1-191) (ABIN969120)
抗原
See all ETV1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-191
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原理
- ETV1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of ETV1 (aa1-191) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions." in: Neoplasia (New York, N.Y.), Vol. 8, Issue 10, pp. 826-32, (2006) (PubMed).
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: "TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions." in: Neoplasia (New York, N.Y.), Vol. 8, Issue 10, pp. 826-32, (2006) (PubMed).
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- ETV1 (Ets Variant 1 (ETV1))
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别名
- ETV1
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背景
- ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.
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基因ID
- 2115
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UniProt
- P50549
抗原
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