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ERN1 抗体 (AA 282-433)

Cited in 3+ publications. This 小鼠 单克隆 anti-ERN1 antibody (Clone 9F2) specifically detects ERN1 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN969116
发货至: 中国
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Quick Overview for ERN1 抗体 (AA 282-433) (ABIN969116)

抗原

See all ERN1 抗体
ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

适用

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宿主

  • 83
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小鼠

克隆类型

  • 73
  • 17
单克隆

标记

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This ERN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

9F2
  • 抗原表位

    • 16
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    AA 282-433

    原理

    ERN1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human ERN1(aa282-433) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Lin, Li, Yasumura, Cohen, Zhang, Panning, Shokat, Lavail, Walter: "IRE1 signaling affects cell fate during the unfolded protein response." in: Science (New York, N.Y.), Vol. 318, Issue 5852, pp. 944-9, (2007) (PubMed).

    Huang, Tan, Yoshida, Mori, Ma, Yen: "Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress." in: Molecular and cellular biology, Vol. 25, Issue 17, pp. 7522-33, (2005) (PubMed).

    Shang, Lehrman: "Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts." in: Biochemical and biophysical research communications, Vol. 317, Issue 2, pp. 390-6, (2004) (PubMed).

  • 抗原

    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

    别名

    ERN1

    背景

    The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

    分子量

    109 kDa

    UniProt

    O75460

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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