ERN1 抗体 (AA 282-433)
Quick Overview for ERN1 抗体 (AA 282-433) (ABIN969116)
抗原
See all ERN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 282-433
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原理
- ERN1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human ERN1(aa282-433) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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IRE1 signaling affects cell fate during the unfolded protein response." in: Science (New York, N.Y.), Vol. 318, Issue 5852, pp. 944-9, (2007) (PubMed).
: "Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress." in: Molecular and cellular biology, Vol. 25, Issue 17, pp. 7522-33, (2005) (PubMed).
: "Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts." in: Biochemical and biophysical research communications, Vol. 317, Issue 2, pp. 390-6, (2004) (PubMed).
: "
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IRE1 signaling affects cell fate during the unfolded protein response." in: Science (New York, N.Y.), Vol. 318, Issue 5852, pp. 944-9, (2007) (PubMed).
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- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
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别名
- ERN1
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背景
- The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.
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分子量
- 109 kDa
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UniProt
- O75460
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途径
- ER-Nucleus Signaling, Unfolded Protein Response
抗原
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