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Dynamin 1 抗体

This anti-Dynamin 1 antibody is a 小鼠 单克隆 antibody detecting Dynamin 1 in WB, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969087
发货至: 中国

Quick Overview for Dynamin 1 抗体 (ABIN969087)

抗原

See all Dynamin 1 (DNM1) 抗体
Dynamin 1 (DNM1)

适用

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宿主

  • 94
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  • 2
小鼠

克隆类型

  • 104
  • 4
单克隆

标记

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This Dynamin 1 antibody is un-conjugated

应用范围

  • 91
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

3G4B6
  • 原理

    Dynamin-1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human Dynamin-1 expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Quan, Robinson: "Rapid purification of native dynamin I and colorimetric GTPase assay." in: Methods in enzymology, Vol. 404, pp. 556-69, (2006) (PubMed).

    Yoo, Jeong, Kwon, Hur, Park, Han: "Activation of dynamin I gene expression by Sp1 and Sp3 is required for neuronal differentiation of N1E-115 cells." in: The Journal of biological chemistry, Vol. 277, Issue 14, pp. 11904-9, (2002) (PubMed).

  • 抗原

    Dynamin 1 (DNM1)

    别名

    Dynamin-1

    背景

    Dynamin-1 (Dyn1), with 864-amino acid protein (about 95 kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.

    分子量

    97 kDa

    基因ID

    1759

    UniProt

    Q05193

    途径

    Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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