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Cytokeratin 5 抗体

This anti-Cytokeratin 5 antibody is a 小鼠 单克隆 antibody detecting Cytokeratin 5 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN969079
发货至: 中国

Quick Overview for Cytokeratin 5 抗体 (ABIN969079)

抗原

See all Cytokeratin 5 (KRT5) 抗体
Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

适用

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宿主

  • 108
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小鼠

克隆类型

  • 93
  • 71
单克隆

标记

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This Cytokeratin 5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1E1
  • 原理

    Cytokeratin 5 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wang, Li: "Adenovirus-mediated RNA interference against collagen-specific molecular chaperone 47-KDa heat shock protein suppresses scar formation on mouse wounds." in: Cell biology international, Vol. 32, Issue 5, pp. 484-93, (2008) (PubMed).

    Nishizawa, Izawa, Inoko, Hayashi, Nagata, Yokoyama, Usukura, Inagaki: "Identification of trichoplein, a novel keratin filament-binding protein." in: Journal of cell science, Vol. 118, Issue Pt 5, pp. 1081-90, (2005) (PubMed).

    Gu, Kim, Ichiki, Park, Nagai, Kitajima: "A usual frameshift and delayed termination codon mutation in keratin 5 causes a novel type of epidermolysis bullosa simplex with migratory circinate erythema." in: The Journal of investigative dermatology, Vol. 121, Issue 3, pp. 482-5, (2003) (PubMed).

  • 抗原

    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

    别名

    Cytokeratin 5

    背景

    Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.

    分子量

    62.3 kDa

    基因ID

    3852

    UniProt

    P13647
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