KRT17 抗体
(1 reference)Quick Overview for KRT17 抗体 (ABIN969058)
抗原
See all KRT17 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CK17 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of CK17 expressed in E. Coli.
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亚型
- IgG2b
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anti-Keratin 17 (KRT17) antibody
KRT17 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (AA 252-393) antibodyKRT17 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (AA 1-432) antibodyKRT17 适用: 人 WB, IF, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2D4-1G9 unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠 WB, IHC, FACS, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal E3 unconjugated
anti-Keratin 17 (KRT17) (AA 133-432) antibodyKRT17 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, Cow, Pig, 山羊 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SPM560 unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (C-Term) antibodyKRT17 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (C-Term) antibodyKRT17 适用: 人, 大鼠, 小鼠, Cow, Pig, 犬, 兔, 绵羊, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 1B12 unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome." in: The American journal of pathology, Vol. 161, Issue 6, pp. 1991-6, (2002) (PubMed).
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: "Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome." in: The American journal of pathology, Vol. 161, Issue 6, pp. 1991-6, (2002) (PubMed).
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- KRT17 (Keratin 17 (KRT17))
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别名
- CK17
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背景
- CK17, also known as KRT17, it is the type I intermediate filament chain keratin 17. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair.
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分子量
- 49 kDa
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基因ID
- 3872
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UniProt
- Q04695
抗原
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