Chitotriosidase 1 抗体 (AA 22-137)
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北京 101111
Quick Overview for Chitotriosidase 1 抗体 (AA 22-137) (ABIN969053)
抗原
See all Chitotriosidase 1 (CHIT1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 22-137
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原理
- CHIT1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for ..." in: Clinical biochemistry, Vol. 40, Issue 5-6, pp. 365-9, (2007) (PubMed).
: "Chitotriosidase analysis in bronchoalveolar lavage of patients with sarcoidosis." in: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders, Vol. 24, Issue 1, pp. 59-64, (2007) (PubMed).
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: "Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for ..." in: Clinical biochemistry, Vol. 40, Issue 5-6, pp. 365-9, (2007) (PubMed).
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- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
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别名
- CHIT1
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背景
- CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
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分子量
- 52 kDa
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基因ID
- 1118
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UniProt
- Q13231
抗原
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