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Chitotriosidase 1 抗体 (AA 22-137)

This anti-Chitotriosidase 1 antibody is a 小鼠 单克隆 antibody detecting Chitotriosidase 1 in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969053
发货至: 中国

Quick Overview for Chitotriosidase 1 抗体 (AA 22-137) (ABIN969053)

抗原

See all Chitotriosidase 1 (CHIT1) 抗体
Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

适用

  • 36
  • 9
  • 3

宿主

  • 32
  • 10
  • 1
小鼠

克隆类型

  • 35
  • 8
单克隆

标记

  • 31
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Chitotriosidase 1 antibody is un-conjugated

应用范围

  • 30
  • 18
  • 13
  • 11
  • 10
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA

克隆位点

1D9G2
  • 抗原表位

    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-137

    原理

    CHIT1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wajner, Michelin, Burin, Pires, Pereira, Giugliani, Coelho et al.: "Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for ..." in: Clinical biochemistry, Vol. 40, Issue 5-6, pp. 365-9, (2007) (PubMed).

    Bargagli, Margollicci, Perrone, Luddi, Perari, Bianchi, Refini, Grosso, Volterrani, Rottoli: "Chitotriosidase analysis in bronchoalveolar lavage of patients with sarcoidosis." in: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders, Vol. 24, Issue 1, pp. 59-64, (2007) (PubMed).

  • 抗原

    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

    别名

    CHIT1

    背景

    CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

    分子量

    52 kDa

    基因ID

    1118

    UniProt

    Q13231
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