This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Wajner, Michelin, Burin, Pires, Pereira, Giugliani, Coelho et al.: "Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for ..." in: Clinical biochemistry, Vol. 40, Issue 5-6, pp. 365-9, (2007) (PubMed).
Bargagli, Margollicci, Perrone, Luddi, Perari, Bianchi, Refini, Grosso, Volterrani, Rottoli: "Chitotriosidase analysis in bronchoalveolar lavage of patients with sarcoidosis." in: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders, Vol. 24, Issue 1, pp. 59-64, (2007) (PubMed).
CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.