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CDC27 抗体

This anti-CDC27 antibody is a 小鼠 单克隆 antibody detecting CDC27 in ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969035
发货至: 中国

Quick Overview for CDC27 抗体 (ABIN969035)

抗原

See all CDC27 抗体
CDC27 (Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27))

适用

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宿主

  • 82
  • 4
小鼠

克隆类型

  • 74
  • 12
单克隆

标记

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This CDC27 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)

克隆位点

5C12
  • 原理

    CDC27 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CDC27 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Goto, Eddy: "Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 42128-38, (2004) (PubMed).

    Koloteva-Levine, Pinchasi, Pereman, Zur, Brandeis, Elroy-Stein: "The Apc5 subunit of the anaphase-promoting complex/cyclosome interacts with poly(A) binding protein and represses internal ribosome entry site-mediated translation." in: Molecular and cellular biology, Vol. 24, Issue 9, pp. 3577-87, (2004) (PubMed).

  • 抗原

    CDC27 (Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27))

    别名

    CDC27

    背景

    Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.

    分子量

    91 kDa

    基因ID

    996

    UniProt

    P30260
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