CD38 抗体
(2 references)Quick Overview for CD38 抗体 (ABIN969023)
抗原
See all CD38 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD38 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human CD38 expressed in E. Coli.
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亚型
- IgG1
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anti-CD38 (AA 1-300) antibody
适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 46-300) antibody适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 43-300) antibody适用: 人 IHC, WB, ELISA 宿主: 小鼠 Monoclonal 5C5C3 unconjugated
anti-CD38 (AA 241-270), (C-Term) antibody适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18001 unconjugated
anti-CD38 (AA 241-270) antibody适用: 人 FACS, IHC, WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (Internal Region) antibody适用: 人, 小鼠, 大鼠 IHC, WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD38 antibody适用: 人 FACS, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal HIT2 unconjugated
anti-CD38 antibody (APC)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 APC
anti-CD38 antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 PE
anti-CD38 (AA 101-200) antibody适用: 小鼠, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Increased association of CD38 with lipid rafts in T cells from patients with systemic lupus erythematosus and in activated normal T cells." in: Molecular immunology, Vol. 43, Issue 7, pp. 1029-39, (2005) (PubMed).
: "Myeloid-lymphoid initiating cells (ML-IC) are highly enriched in the rhodamine-c-kit(+)CD33(-)CD38(-) fraction of umbilical cord CD34(+) cells." in: Experimental hematology, Vol. 30, Issue 6, pp. 582-9, (2002) (PubMed).
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: "Increased association of CD38 with lipid rafts in T cells from patients with systemic lupus erythematosus and in activated normal T cells." in: Molecular immunology, Vol. 43, Issue 7, pp. 1029-39, (2005) (PubMed).
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- CD38
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背景
- CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.
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分子量
- 34 kDa
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基因ID
- 952
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UniProt
- P28907
抗原
-
