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Cyclin B1 抗体

This anti-Cyclin B1 antibody is a 小鼠 单克隆 antibody detecting Cyclin B1 in WB, ELISA, FACS 和 ICC. Suitable for 人 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969006
发货至: 中国

Quick Overview for Cyclin B1 抗体 (ABIN969006)

抗原

See all Cyclin B1 (CCNB1) 抗体
Cyclin B1 (CCNB1)

适用

  • 201
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人, 大鼠

宿主

  • 168
  • 41
  • 1
小鼠

克隆类型

  • 148
  • 62
单克隆

标记

  • 110
  • 9
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  • 4
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  • 1
  • 1
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  • 1
This Cyclin B1 antibody is un-conjugated

应用范围

  • 138
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  • 1
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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

5G6
  • 原理

    CCNB1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CCNB1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Chou, Yen, Lee, Chen: "Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17833-45, (2010) (PubMed).

    Gustafsson, Zhao, Gustafsson, Dahlman-Wright: "RBCK1 drives breast cancer cell proliferation by promoting transcription of estrogen receptor alpha and cyclin B1." in: Cancer research, Vol. 70, Issue 3, pp. 1265-74, (2010) (PubMed).

  • 抗原

    Cyclin B1 (CCNB1)

    别名

    CCNB1

    背景

    The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. (provided by RefSeq) It has higher expression in tumor tissues .

    分子量

    60 kDa

    基因ID

    891

    UniProt

    P14635

    途径

    Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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